Back to normal version
Home > About breast cancer > Treatment > Drug therapy > Chemotherapy

AC (doxorubicin, cyclophosphamide)

If you have AC, you'll have four to six cycles of treatment, and each cycle is given once every 3 weeks. So that's a total of three to four months.
On day 1 of each cycle, you'll have injections of doxorubicin and cyclophosphamide. This will be repeated at the start of your next cycle, three weeks later.

AC includes doxorubicin - one of a group of drugs called anthracyclines. There is evidence that chemotherapy which includes an anthracycline works better than CMF but anthracyclines tend to have more severe side effects.

Main side effects

  • Nausea and vomiting
  • Tiredness
  • Mouth ulcers
  • Diarrhoea
  • Infections
  • Complete loss of hair
  • Itchy rash and nail changes
  • Bladder irritation
  • Loss of fertility
A lot can be done to relieve these problems. See dealing with chemotherapy side effects.

To find out more about this treatment, try the CancerBACUP website.

Top of page    Print version    Send to a friend